CM2350 Air compressor install

[DPS567180]

Greetings all. I am a new member and this is my first post. I have been reading these threads for years though and have learned quite a bit. So it looks like I'm going to have to replace my air compressor and I have two questions.
1-do I have to drain all of the coolant And if not how many gallons do you think I need to drain?
2-does the CM2350 engine require setting timing?
Truck is a 2015 international ProStar with CM2350 ISX engine. Thanks in advance.