ISX will not start.

[Dcolumbia]

I have a friend that has been running quite awhile with the lift pump not working, about 20,000 miles or so. He finally tracked down the inline fuse and replaces it. Last time they did his PM service they charged him extra to bleed the fuel system since the pump wasn't working so he decided he would fix it before the next PM. Replaced the fuse, pump ran but very noisy. He made it about 60 miles, shut the truck off and was out of the truck maybe 10 minutes. Now the truck won't start. Lift pump still comes on and is very noisy. Checked ecm breaker, it was good. Can the lift pump cause the high pressure pump to just go out? He is being towed right now. Trying to see if it could be anything simple. He has an 09 Prostar cm 871.